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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18639 | Cl-C6-PEG4-O-CH2COOH | PROTAC Linker 4 | Others |
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an effective pegylated PROTAC linker, which is often used in PROTAC synthesis of chloroanes (HaloPROTACs). | |||
T18614 | Bis-Tos-PEG4 | Tetraethylene glycol di(p-toluenesulfonate),PROTAC Linker 16,1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Others , PROTAC Linker |
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker. Bis-Tos-PEG4 can be used in the synthesis of PROTACs. | |||
T14408 | Azido-PEG1-CH2CO2H | Others , PROTAC Linker | |
Azido-PEG1-CH2CO2H is a PROTAC linker that refers to an alkyl/ether combination. Azido-PEG1-CH2CO2H can be used to synthesize PROTAC BRD4 Degrader-1[1]. | |||
T18391 | N-Boc-4-pentyne-1-amine | Others , PROTAC Linker | |
N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound utilized in the synthesis of PROTAC MG-277[1]. | |||
T18807 | Thalidomide-NH-C4-NH-Boc | E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase | |
Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker. | |||
T16658 | Boc-NH-PEG4 | PROTAC Linker 12 | Others |
Boc-NH-PEG4, also known as PROTAC Linker 12, is a PEG-based linker compound utilized for the synthesis of PROTACs[1]. | |||
T18628 | Tos-PEG4-NH-Boc | PROTAC Linker 7 | Others |
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker used for the synthesis of PROTACs[1]. | |||
T15529 | Hydroxy-PEG4-(CH2)2-Boc | PROTAC Linker | |
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc can also be used in the synthesis of PROTAC. | |||
T17653 | Boc-NH-C4-acid | Others , PROTAC Linker | |
Boc-NH-C4-acid is a PROTAC linker belonging to the Alkyl/ether class, which can be used for the synthesis of PROTAC1 and can degrade EED, EZH2, and SUZ12 in PRC2. | |||
T15919 | M-PEG7-4-nitrophenyl carbonate | Others , PROTAC Linker | |
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. | |||
T18546 | (+)-Biotin-ONP | (+)-Biotin 4-nitrophenyl ester | Others , PROTAC Linker |
(+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs. | |||
T14271 | Aminooxy-PEG4-alcohol | Others , PROTAC Linker | |
Aminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker. | |||
T17326 | 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide | 2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide | Others , PROTAC Linker |
2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide (2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide) is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. | |||
FL0195 | N-Boc-4-hydroxy-L-proline methyl ester | ||
N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2]. | |||
T9386 | 2-(2,6-dioxopiperidin-3-yl)-4-((9-hydroxynonyl)oxy)isoindoline-1,3-dione | Others | |
2-(2,6-dioxopiperidin-3-yl)-4-((9-hydroxynonyl)oxy)isoindoline-1,3-dione is a PROTAC linker that can be used in the synthesis of PROTACs. | |||
T17325 | Pomalidomide-PEG4-C-COOH | Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1 | Others , E3 Ligase Ligand-Linker Conjugate |
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology. | |||
T18595 | Dasatinib carbaldehyde | PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde | Others , Ligands for Target Protein for PROTAC |
Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1]. | |||
T7755 | Thalidomide 4-fluoride | E3 ligase Ligand 4 | IRAK , Ligand for E3 Ligase |
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) ... | |||
T17921 | (S,R,S)-AHPC-PEG4-N3 | VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 | Others , PROTAC Linker |
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both c... | |||
T40030 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | halidomide-linker 6 | E3 Ligase Ligand-Linker Conjugate |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate. |